Histopathology and Immunophenotype of the Spleen During Acute Antibody-Mediated Rejection
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چکیده
منابع مشابه
Acute antibody-mediated rejection after intestinal transplantation
AIM To investigate the incidence, risk factors and clinical outcomes of acute antibody-mediated rejection (ABMR) after intestinal transplantation (ITx). METHODS A retrospective single-center analysis was performed to identify cases of acute ABMR after ITx, based on the presence of donor-specific antibody (DSA), acute tissue damage, C4d deposition, and allograft dysfunction. RESULTS Acute AB...
متن کاملAcute antibody-mediated rejection after lung transplantation.
BACKGROUND Antibody-mediated rejection (AMR) after lung transplantation remains enigmatic, and there is no consensus on the characteristic clinical, immunologic and histologic features. METHODS We performed a retrospective, single-center cohort study and identified cases of acute AMR based on the presence of circulating donor-specific human leukocyte antigen (HLA) antibodies (DSA), histologic...
متن کاملAntibody-mediated rejection.
The introduction of both complement 4d (C4d) staining in renal allograft biopsies and sensitive methods to detect anti-human leukocyte antigen antibodies, such as single antigen bead flow assays, into tissue-typing techniques have shown the importance of antibody-mediated alloimmune response in kidney transplantation. The use of these sensitive methods, combined with the increased number of tra...
متن کاملAntibody Mediated Rejection of the Cardiac Allograft
Antibody mediated rejection (AMR), also known as B-cell mediated rejection or humoral rejection, of the cardiac allograft was first clinically described in the late 1980’s (Herskowitz et al., 1987) followed shortly thereafter by pathologic evidence to support a unique rejection process apart from cellular mechanisms (Hammond et al., 1989). This is in contrast to the progression of knowledge reg...
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ژورنال
عنوان ژورنال: American Journal of Transplantation
سال: 2010
ISSN: 1600-6135,1600-6143
DOI: 10.1111/j.1600-6143.2010.03067.x